Deleterious Effects of Increased Intra-Abdominal Pressure on Kidney Function

Effects of increased intra-abdominal pressure on central circulation.

BACKGROUND In an experimental model we investigated the effects of a gradual increase in intra-abdominal pressure (IAP) on the central circulation. METHODS Seven pigs were anaesthetized, mechanically ventilated and instrumented. IAP was gradually increased by 5 mm Hg up to 30 mm Hg by abdominal banding in normovolaemic animals, and then they were made hypovolaemic after blood withdrawal. Righ...

Effects of increased intra-abdominal pressure and volume expansion on renal function in the rat.

BACKGROUND The effects of increased intra-abdominal pressure (IAP) and volume expansion on renal function in the rat were studied to gain more knowledge of the oliguria seen during laparoscopic procedures and to reduce the detrimental renal effects of IAP. METHODS IAP was elevated to 5 or 10 mmHg by insufflation of CO(2) and maintained for 2 h in anaesthetized and mechanically ventilated rats...

Long term effects of kidney donation on blood pressure and kidney function of donors

Introduction: Kidney transplantation from a live donor has many advantages, but the donor should undergo a major surgery and accept potential morbidity and mortality. In this study, we evaluated the long term effects of nephrectomy on renal function and blood pressure of kidney donors. Methods: In this cross-sectional study, we assessed 195 kidney donors. The controls were 100 healthy individu...

The Effect of Increased Intra-abdominal Pressure on Renal Function in Man.

Increased intra-abdominal pressure in acute kidney injury: a cause or an effect?

The detrimental effects of increased intra-abdominal pressure (IAP) on kidneys and other intra-abdominal organs have been known for a long time, particularly in postoperative conditions [1]. In recent decades, the significance of intra-abdominal hypertension (IAH) has been increasingly recognized because it is much more prevalent than expected and is associated with increased morbidity and mort...